Dr Heather Verkade

Lecturer

Bsc (hons)
Ph D (University of Melbourne, Peter MacCallum Cancer Institute)
Telephone: +61-3-9905-4663
Fax: +61-3-9905-5613
E-mail: heather.verkade@sci.monash.edu.au

• Morphogenetic movements during zebrafish intestinal development
• Endodermal cell migration
• Cell polarity during cell movements

See the first 18 hours of zebrafish development

See more about the zebrafish as a model organism

Projects for prospective students

• de Jong-Curtain TA, Hall NE, Crowhurst MO,  Layton JE, Trotter AJ, Verkade H, Parslow AC, Shepherd IT, Zon LI, Stainier DYR, Lieschke GL, Heath JK. (2009) A nonsense mutation in elys is responsible for the intestinal epithelium and eye abnormalities in the zebrafish mutant, flotte lotte. Gastroenterology. 136 (3): 902-11
• Verkade H, Heath JK. (2009) Wnt signalling mediates diverse developmental processes in zebrafish. In Methods in Molecular Biology Vol. 469 Wnt Signaling, Vol. 2: Pathway models (Ed. Elizabeth Vincan, Humana Press) pp.225-251 (Book Chapter)
• Hogan BM, Verkade H, Lieschke GJ, Heath JK. (2009) Manipulation of gene expression during zebrafish embryonic development using transient approaches. In Methods in Molecular Biology Vol. 469. Wnt Signaling, Vol.2: Pathway models (Ed. Elizabeth Vincan, Humana Press) pp273-300. (Book Chapter)
• Osborne N, Brand-Arzamendi K, Ober EA, Jin S-W, Verkade H, Glickman Holtzman N, Yelon D, Stainier DYR. (2008) The spinster homologue, Two of Hearts, is required for sphingosine 1-phosphate signaling in zebrafish. Current Biology. 18, (23): 1882-1888
• Noël ES, Casal-Sueiro A, Verkade H, and Ober EA. (2008) Organ-specific requirements for Hdac1 in liver and pancreas formation.  Dev.Biol. 322:237-250
• Munson C,  Huisken J, Bit-Avragim N, Kuo T, Dong PD, Verkade H, Ober EA, Abdelilah-Seyfried S, Stainier DYR. (2008) Regulation of neurocoel morphogenesis by Pard6ýb. Dev. Biol. 324:41-54
• Mizoguchi T, Verkade H, Heath JK, Kuroiwa A, Kikuchi Y.  (2008) Sdf1-Cxcr4 signaling controls endoderm cell migration in the zebrafish gastrula. Development 135:2521-2529
• Shin CH, Chung W-S, Hong S-K, Ober EA, Verkade H, Field HA, Huisken J, Stainier DYR. (2008) Multiple roles for med12 in endoderm development. Dev. Biol 317: 467-479
• Wilkins SJ, Yoong S, Verkade H, Mizoguchi T, Plowman SJ, Hancock JF, Kikuchi Y, Heath JK, Perkins AC. (2008) Mtx2 directs zebrafish morphogenetic movements during epiboly by regulating microfilament formation.  Dev. Biol 314 (1): 12-22
• Ober EA, Verkade H, Field HA, Stainier DYR. (2006) Mesodermal Wnt2b signaling positively regulates liver specification. Nature 442(7103): 688-91
• Beis D, Bartman T, Jin S-W, Scott IC, D'Amico LA,  Ober EA, Verkade H, Frantsve J, Field H, Wehman A, Baier H, Tallafuss A, Bally-Cuif L, Chen J-N, Stainier DYR, Jungblut B. (2005) Genetic and cellular analysis of zebrafish atrioventricular cushion and valve development. Development, 132, 4193-4204
• Kikuchi Y, Verkade H, Reiter JF, Kim CH, Chitnis AB, Kuroiwa A, Stainier DYR. (2004) Notch signalling can regulate endoderm formation in zebrafish. Dev Dyn., 299, 756 - 762
• Verkade HM, Bugg SJ, Lindsay H, Carr AM, O'Connell MJ. (1999) Rad18 is required for DNA repair and checkpoint responses in fission yeast. Mol. Biol. Cell.,  10, 2905-2918