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Prof. John Hamill

Professor

Ph.D. University of Nottingham

Telephone: +61-3-9905-3850
Fax: +61-3-9905-5613
E-mail: john.hamill@sci.monash.edu.au

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Prof John Hamill
International Refereed Journals
  1. Patnaik G, Cocking E.C, Hamill, J.D., Pental D. (1982) A simple procedure for the manual isolation and identification of plant heterokaryons. Plant Science Letters 24 : 105-110
  2. Hamill J.D, Pental D.,Cocking E.C., Müller A.J. (1983) Production of a nitrate reductase deficient streptomycin resistant double mutant of Nicotiana tabacum for somatic hybridization studies. Heredity 50 : 197-200
  3. Hamill, J.D., Patnaik, G. Pental D., Cocking E.C. (1984) The culture of manually isolated heterokaryons of Nicotiana tabacumand Nicotiana rustica. Proceedings Indian Academy Science (Plant Science) 93 : 317-327
  4. Hamill, J.D., Pental D., Cocking E.C. (1984) The combination of a nitrate reductase deficient nuclear genome with a streptomycin resistant chloroplast genome in Nicotiana tabacum by protoplast fusion. Journal of Plant Physiology 115 : 253-261
  5. Pental D., Hamill J.D., Cocking E.C. (1984) Somatic hybridization using a double mutant of Nicotiana tabacum. Heredity 53 : 79-83
  6. Hamill, J.D., Pental D., Cocking E.C. (1985) Analysis of fertility in somatic hybrids of Nicotiana tabacum and Nicotiana rusticaand progeny over two generations. Theoretical & Applied Genetics 71 : 487-490
  7. Pental, D., Hamill, J.D., Pirrie, A., Cocking, E.C. (1986). Somatic hybridization between Nicotiana tabacum and Petunia hybrida. Recovery of plants with P. hybrida nuclear genome and N. tabacum chloroplast genome. Molecular & General Genetics 202 : 342-347.
  8. Hamill, J.D., Cocking, E.C. (1986). The control of pH and the effect on ammonium utilization by nitrate reductase deficient plants, cells and protoplasts of Nicotiana tabacum. Journal of Plant Physiology 123 : 289-298.
  9. Hamill, J.D., Parr, A.J., Robins, R.J., Rhodes, M.J.C. (1986). Secondary product formation by cultures of Beta vulgaris and Nicotiana rustica transformed with Agrobacterium rhizogenes. Plant Cell Reports 5 : 111-114.
  10. Hamill, J.D., Ahuja, P.S., Davey, M.R., Cocking, E.C. (1986). Protoplast derived streptomycin resistant plants of the forage legume Onobrychis viciifolia Scop. (sainfoin). Plant Cell Reports 5 : 439-441.
  11. Hamill, J.D., Watts, J.W., King, J.M. (1987). Somatic hybridization between Nicotiana tabacum and Nicotiana plumbaginifolia by electrofusion of mesophyll protoplasts. Journal of Plant Physiology 129 : 111-118.
  12. Hamill, J.D., Parr, A.J., Robins, R.J., Rhodes, M.J.C., Walton, N. (1987). New routes to secondary products. Bio/Technology 5 : 800-804.
  13. Parr, A.J., Hamill, J.D. (1987). Relationships between the biosynthetic capacities of Agrobacterium rhizogenes transformed hairy roots and intact, uninfected plants of Nicotiana species. Phytochemistry 26 : 3241-3245.
  14. Furze, J., Hamill, J.D., Parr, A.J., Robins, R.J., Rhodes, M.J.C. (1987). Evaluation of the variability found in hairy root cultures of Nicotiana rustica after regeneration from protoplasts. Journal of Plant Physiology 131 : 237-246.
  15. Payne, J., Hamill, J.D., Robins, R.J. and Rhodes M.J.C. (1987). Production of hyoscyamine by hairy root cultures of Datura stramonium Planta Medica 53 : 474-478
  16. Hamill, J.D., Prescott, A., Martin, C. (1987). Assessment of the efficiency of co-transformation by the T-DNA of disarmed binary vectors derived from Agrobacterium tumefaciens and the T-DNA from A. rhizogenes. Plant Molecular Biology 9 : 573-584.
  17. Hamill, J.D., Mariotti, D. (1987). Factors affecting chlorate sensitivity in cell cultures of Medicago sativa. Journal of Plant Physiology 128 : 425-432.
  18. Aird, E.L.H., Hamill, J.D., Rhodes, M.J.C. (1988). Cytogenetic analysis of hairy root cultures from a number of plant species transformed by Agrobacterium rhizogenes. Plant Cell, Tissue and Organ Culture 15 : 47-57.
  19. Parr, A.J., Peerless, A.C.J., Hamill, J.D., Walton, N.J., Robins, R.J., Rhodes, M.J.C. (1988). Alkaloid production by transformed root cultures of Catharanthus roseus. Plant Cell Reports 7 : 309-312.
  20. Hamill, J.D., Rhodes, M.J.C. (1988). A spontaneous, light independent and prolific plant regeneration response from hairy roots of Nicotiana hesperis transformed by Agrobacterium rhizogenes. Journal of Plant Physiology. 133 : 506-509.
  21. Hamill, J.D., Robins, R.J., Rhodes, M.J.C. (1989). Alkaloid production by transformed root cultures of Cinchona ledgeriana. Planta Medica 55 : 354-357.
  22. Spencer, A., Hamill, J.D., Rhodes, M.J.C. (1990). Production of terpenes by differentiated shoot cultures of Mentha citrata transformed by Agrobacterium tumefaciens T37. Plant Cell Reports 8 : 601-604.
  23. Hamill, J.D., Robins, R.J., Parr, A.J., Furze, J., Evans, D.J., Rhodes, M.J.C. (1990). Overexpressing a yeast ornithine decarboxylase gene in transgenic roots of Nicotiana rustica can lead to enhanced nicotine accumulation. Plant Molecular Biology 15 : 27-38.
  24. Benson, E., Hamill, J.D. (1991). Cryopreservation and postfreeze molecular and biosynthetic stability in transformed roots of Beta vulgaris and Nicotiana rustica. Plant Cell, Tissue and Organ Culture 24 : 163-172.
  25. Robins, R.J., Hamill, J.D., Bent, E.G., Evans, D.M. (1991). A rapid and quantitative method for the determination of chloramphenicol-3-O-acetyltransferase activity in transgenic plants. Methods in Molecular and Cellular Biology 2 : 91-94.
  26. Robins, R.J., Walton, N.J., Hamill, J.D., Parr, A.J., Rhodes, M.J.C. (1991). Strategies for the genetic manipulation of alkaloid producing pathways in plants. Planta Medica 57 : 527-535.
  27. Hamill, J.D., Rounsley, S., Spencer, A., Todd, G., Rhodes, M.J.C. (1991). The polymerase chain reaction in plant transformation studies. Plant Cell Reports 10 : 221-224.
  28. Spencer, A., Hamill, J.D., Rhodes, M.J.C. (1992). In vitro biosynthesis of monoterpenes by Agrobacterium transformed shoot cultures of two Mentha species. Phytochemistry 32 : 911-919.
  29. Hamill, J.D. (1993). Alterations in auxin and cytokinin metabolism of higher plants due to expression of specific genes from pathogenic bacteria. Australian Journal of Plant Physiology 20:405-424.
  30. Kuang, J., Gaff, D.F., Gianello, R.D., Blomstedt, C.K., Neale, A.D., Hamill, J.D. (1995) Changes in in vivo protein complements in drying leaves of the desiccation-tolerant grass Sporobolus stapfianus and the desiccation-sensitive grass Sporobolus pyramadalis. Australian Journal of Plant Physiology 22 : 1027-1034
  31. Lidgett, A.J., Moran, M., Wong, K.A.L., Furze, J., Rhodes, M.J.C., Hamill, J.D. (1995). Isolation and expression of pattern of a cDNA encoding a cathepsin B-like protease from Nicotiana rustica. Plant Molecular Biology 29: 379-384.
  32. Pelosi, A., Lee, M.C.S., Chandler, S.F., Hamill, J.D. (1995). Hormonal control of root primordia differentiation and root formation in cultured explants of Eucalyptus globulus seedlings. Australian Journal of Plant Physiology 22 : 409-415.
  33. Subroto, M.A., Hamill, J.D. and Doran, P.M. (1995). Growth kinetics and stoichiometry of Mentha citrata shooty teratomas transformed by Agrobacterium tumefaciens. Biotechnology Letters 17 : 427-432.
  34. Subroto, M.A., Hamill, J.D. and Doran, P.M. (1996). Development of shooty teratomas from several solanaceous plants: growth kinetics, stoichiometry and alkaloid production. Journal of Biotechnology 45 : 45-57.
  35. Subroto, M.A., Kwok, K.H., Hamill, J.D. and Doran, P.M. (1996). Coculture of genetically transformed roots and shoots for synthesis, translocation and biotransformation of secondary metabolites. Biotechnology and Bioengineering 49 : 481-494.
  36. Ng, A., Blomstedt, C.K., Gianello, R., Neale, A.D., Hamill, J.D. and Gaff, D. (1996). A lowly expressed cDNA from Sporobolus stapfianus encoding a sulphate transporter protein. Plant Physiology 111 : 651.
  37. Blomstedt C.K., Gianello R.D., Hamill J.D., Neale A.D. and Gaff D.F (1998). Drought-stimulated genes correlated with desiccation tolerance of the resurrection grass Sporobolus stapfianus Plant Growth Regulation 24 : 153-161.
  38. Blomstedt, C., Gianello, R., Hamill, J.D., Gaff, D. and Neale, A. (1998). Differential gene expression in desiccation-tolerant and desiccation-sensitive tissue of the resurrection grass Sporobolus stapfianus. Australian Journal of Plant Physiology 28 : 937-946
  39. Bandyopadhyay, S., Cane, K., Rasmussen, G and Hamill, J.D. (1999) important temperate eucalypt species - Eucalyptus nitens and E. globulus. Plant Science 140 : 189-198
  40. Neale, A.D., Blomstedt, C.K., Bronson, P., Le, T.-N., Guthridge, K., Evans, J., Gaff, D.F. and Hamill, J.D. (2000) The isolation of genes from the resurrection grass Sporobolus stapfianus which are induced during severe drought stress Plant Cell and Environment 23 : 265-277 (pdf 1.1mb)
  41. Bandyopadhyay, S. and Hamill, J.D. (2000) Ultrastructural studies of somatic embryos of Eucalyptus nitens and comparisons with zygotic embryos found in mature seeds Annals of Botany 86 : 237-244 (pdf 384kb)
  42. Sinclair, S.J., Murphy, K. J., Birch, C.D and Hamill, J.D. (2000 )Molecular Characterisation of Quinolinic Acid Phosphoribosyltransferase (QPRTase) In Nicotiana Plant Molecular Biology 44 : 603 - 617 (pdf 359kb)
  43. Chintapakorn Y and Hamill J.D. (2003) Antisense-mediated down regulation of putrescine N-methyltransferase activity in transgenic Nicotiana tabacum L. can lead to elevated levels of anatabine at the expense of nicotine Plant Molecular Biology 53 : 87 - 105 (pdf 902kb)
  44. Sinclair SJ, Johnson RJ and Hamill, JD (2004) Analysis of wound-induced expression in Nicotiana species with contrasting alkaloid profiles. Functional Plant Biology 31: 721- 729 (pdf 2.5mb)
  45. Cane KA, Mayer M, Michael AJ, Lidgett AJ and. Hamill JD (2005) Molecular analysis of alkaloid metabolism in AABB vs aabb genotype Nicotiana tabacum L in response to wounding of aerial tissues and methyl jasmonate-treatment of cultured roots. Functional Plant Biology 32 : 305 - 320 (pdf 522kb)
  46. Chintapakorn Y and Hamill J.D. (2007) Antisense-mediated reduction in ADC activity causes minor alterations in the alkaloid profile of cultured hairy roots and regenerated transgenic plants of Nicotiana tabacum Phytochemistry. 68 : 2465–2479 (pdf 1mb)
  47. Le T N-G., Blomstedt C.K., Kuang J., Tenlen J., Gaff D.F., Hamill J.D. and Neale A.D. (2007) Desiccation-tolerance specific gene expression in leaf tissue of the resurrection plant Sporobolus stapfianus. Functional Plant Biology. 34 : 1–12 (pdf 260kb)
  48. DeBoer, K.D., Lye J.C., Aitken, C.D., Su A K-K, and Hamill J.D. (2009) The A622 gene in Nicotiana glauca (tree tobacco): evidence for a functional role in pyridine alkaloid synthesis. Plant Molecular Biology, 69 : 299–312. (Note that the results of this paper were featured on the front cover of the Fe 2009. issue of Pmb) (pdf 680kb)
  49. Gaff D.F., Blomstedt C.K., Neale A.D., Le T.N., Hamill J.D. and Ghazempour H.R. (2009) Sporobolus stapfianus, a model desiccation-tolerant grass. Functional Plant Biology 36 : 589 - 599 (pdf 1.8mb)
  50. Blomstedt C.K., Griffiths C.A., Fredericks D.P., Hamill J.D., Gaff D.F. and Neale A.D. (2010) The resurrection plant Sporobolus stapfianus: An unlikely model for engineering enhanced plant biomass? Plant Growth Regulation 62 : 217 - 232 (pdf 620kb)
  51. DeBoer K.D., Dalton H.L., Edwards F.J. and Hamill J.D. (2011) RNAi-mediated down-regulation of ornithine decarboxylase (ODC) leads to reduced nicotine and increased anatabine levels in transgenic Nicotiana tabacum L. Phytochemistry, 72 : 344-355 (pdf 1.56mb)
  52. De Boer K.D., Tilleman S, Pauwels L, Bossche R.V., De Sutter V, Vanderhaeghen R, Hilson P, Hamill J.D. and Goossens A. (2011) APETALA2/ETHYLENE RESPONSE FACTOR and basic helix–loop–helix tobacco transcription factors cooperatively mediate jasmonate-elicited nicotine biosynthesis. The Plant Journal, 66 : 1053-1065 (pdf 364kb)
  53. Pelosi A, Shepherd R, De Guzman G, Hamill JD, Meeusen E, Sanson G, Walmsley AM (2011) The Release and Induced Immune Responses of a Plant-made and Delivered Antigen in the Mouse Gut. Current Drug Delivery (in press) (pdf 397kb)
  54. Blomstedt CK, Gleadow RM, O'Donnell N, Naur P, Jensen K, Laursen T, Olsen CE, Stuart P, Hamill JD, Møller BL, Neale AD (2011) A combined biochemical screening TILLING identifies a mutation in the cytochrome P450 CYP79A1 gene resulting in acyanogenic forage sorghum (Sorghum bicolor L. Moench). The Plant Biotechnology Journal (in press - DOI: 10.1111/j.1467-7652.2011.00646.x (Note this paper will be featured on front cover of the relevant issue) (pdf 876kb)
  55. De Guzman G*, Walmsley AM, Webster DE, Hamill JD. Hairy roots cultures from different Solanaceous species have varying capacities to produce E. coli B-subunit heat-labile toxin antigen Biotechnology Letters (in press - DOI 10.1007/s10529-011-0710-9) (pdf 644kb)
Contributions to books and conference proceedings(full papers)
  1. Rhodes, M.J.C., Robins, R.J., Parr, A.J., Hamill, J.D. (1987). Secondary product formation in plant cell cultures. J. Applied Bacteriology Symposium Supplement 1055-1145.
  2. Hamill, J.D., Cocking, E.C. (1988). Somatic hybridization and its use in agriculture. In: Plant Cell Biotechnology, Pais, M.S.S., Mavituna, F., Novais, J.M. (eds) N.A.T.O. ASI Series 18:21-42.
  3. Hamill, J.D. (1988). Plant genetic transformation methods. In :- Manipulating secondary metabolism in culture. Robins, R.J., Rhodes, M.J.C. (eds) Cambridge University Press pp 114-122.
  4. Hamill, J.D., Evans, D., Robins, R.J., Rhodes, M.J.C., Prescott, A., Martin, C. (1988). Foreign gene insertion into hairy roots with binary vectors and Agrobacterium rhizogenes:- potential for genetic manipulation of plant secondary metabolism in culture. In :- Robins, R.J., Rhodes, M.J.C. (eds) Cambridge University Press pp 145-153.
  5. Draper, J., Scott, R., Hamill, J.D. (1988). Transformation of dicotyledonous plants using the Ti plasmid of Agrobacterium tumefaciens and the Ri plasmid of A. rhizogenes. In:- Plant genetic transformation and gene expression - A laboratory manual. Draper, J., Scott, R., Armitage, P., Walden, R. (eds). Blackwell Scientific Publications, Oxford, Edinburgh, Boston, , Melbourne pp 69-190.
  6. Hamill, J.D., Rounsley, S., Spencer, A., Todd, G., Rhodes, M.J.C. (1990). The use of the polymerase chain reaction to detect specific sequences in transformed plant tissues. In:- Progress in Plant Cellular and Molecular Biology: Current Plant Science and Biotechnology in Agriculture. Nijkamp, H.J.J., Van der Plas, L.H.W, van Aartrijk, J. (eds). Kluwer Academic Publishers, pp. 183-188.
  7. Hamill, J.D., Robins, R.J., Parr, A.J., Evans, D.M., Furze, J.M., Bent, E.G., Rhodes, M.J.C. (1990). The effects of over-expressing the yeast ornithine decarboxylase gene upon the nicotine and polyamine levels in transformed roots of Nicotiana rustica. In:- Progress in Plant Cellular and Molecular Biology: Current Plant Science and Biotechnology in Agriculture. Nijkamp, H.J.J., Van der Plas, L.H.W., Van Aartrijk, J. (eds). Kluwer Academic Publishers, pp. 732-737.
  8. Spencer, J.A., Hamill, J.D., Reynolds, J., Rhodes, M.J.C. (1990). Production of terpenes by transformed differentiated shoot cultures of Mentha piperita citrata and M. piperita vulgaris. In:-Progress in Plant Cellular and Molecular Biology: Current Plant Science and Biotechnology in Agriculture. Nijkamp, H.J.J., Van der Plas, L.H.W., Van Aartrijk, J. (eds). Kluwer Academic Publishers, pp. 619-624.
  9. Hamill, J.D., Robins, R.J., Parr, A.J., Spencer, J.A., Rhodes, M.J.C. (1990). The use of transformed organ cultures for the study and genetic manipulation of plant secondary metabolism. In:- From Genes to Bioproducts - Proceedings of 3rd Spanish Congress of Biotechnology, PPU Press, Murcia, Spain. Iborra, J.L. (ed), pp. 173-179.
  10. Rhodes, M.J.C., Spencer, A., Hamill, J.D., Robins, R.J. (1992). Flavour improvement through plant cell culture. In:- Biotransformation of Flavours. Charlwood, B.V., Patterson, R.W., McLeod, G., Williams, A.A. (eds). Royal Society Chemistry, London, pp. 42-64.
  11. Hamill, J.D., Spencer, A., Rhodes, M.J.C. (1992). Production of phytochemicals by shooty teratoma cultures grown in vitro. Proc. 10th Australian. Biotechnology Conference. Prince, I.G. (ed), pp. 366-371.
  12. Spencer, A., Hamill, J.D., Rhodes, M.J.C. (1992). Transformation in Mentha. In:- Plant Protoplast and Genetic Engineering. Bajaj, Y.P.S. (ed). Springer-Verlag, Berlin, Heidelberg, pp. 278-293.
  13. Hamill, J.D., Rhodes, M.J.C. (1993). Manipulating secondary metabolism in culture. In:- Plant Biotechnology III - Biosynthesis and Manipulation of Plant Products. Grierson, D. (ed). Blackie, London, Glasgow, Melbourne, pp. 178-209.
  14. Hamill, J.D., Chandler, S.F. (1994). Use of root culture for gene expression and root development studies. In:- Biology of Adventitious Root Formation. Davis, T.D. and Haissig, B. (eds). Plenum Publishing Corp., New York, pp. 163-180.
  15. Hamill, J.D., Parr, A.J. (1994). Methods for producing alkaloids in root cultures and analysis of the products. In:- Modern Methods of Plant Analysis, Vol. 15. Jackson, J.F. and Linskens, H.F. (eds). Springer-Verlag, Berlin, London, pp. 191-214.
  16. Pelosi, A., Chow, K.F.C., Lee, M.C.S., Chandler, S.F., Hamill, J.D. (1995). Effects of phytohormones on lateral root differentiation in Eucalyptus globulus and transgenic Nicotiana tabacum seedlings. In:- Current Issues of Plant Molecular and Cellular Biology, Terzi, M., Cella, R. and Falavigna, A. (eds). Kluwer Academic Publishers, pp. 439-499.
  17. Hamill, J.D., Lidgett, A.J. (1997). Hairy Root Cultures - opportunities and key protocols for studies in metabolic engineering. In:- Hairy Roots, Doran, P.M. (ed). Gordon and Breach/Harwood Academic, UK, pp. 1-30
  18. Subroto, M.A., Mahagamasekera, Kwok, K.H., Hamill, J.D., Doran, P.M. (1997). Co-Culture of hairy roots and shooty teratomas. In:- Hairy Roots, Doran, P.M. (ed). Gordon and Breach/Harwood Academic, UK, pp. 81-88.
  19. Hamill, J.D. (1999)
    (i) Gene regulation during development (section 10.3.3.a. pp 332 - 333);
    (ii) Gene expression modified by external factors (section 10.3.4. pp 335 - 336),
    (iii) Modified genomes : genetic engineering (section 10.4.1. pp 339 - 349). In :- Plants in Action - Adaption in nature, performance in culture. Atwell, B J., Kriedemann, P.E. III.and Turnbull, C.G. (eds); Macmillan Australia,1999
  20. Gianello, R.D., Kuang,J., Gaff, D.F., Ghasempour, H.R., Blomstedt, C.K., Hamill, J.D. and Neale, A.D. (1999). Proteins correlated with desiccation tolerance in a resurrection grass Sporobolus stapfianus. In:- Plant responses to environmental stress. Smallwood, M.F., Calvert,C.M. and Bowles,D.J. (eds) BIOS Scientific Publishers, Oxford; 1999; pp 161 - 166