Project Title
Efficient production of health related vaccines in in-vitro grown plant tissues using novel species as hosts
Abstract
The use of plants as an efficient system to produce health related proteins (e.g. vaccines) is becoming a more feasible alternative to current production systems, by providing advantages in storage, stability and delivery. Despite the numerous advantages, progress beyond phase 1 human trials is non-existent, with one of the main limitations being that the production efficiency of this system is non high enough to warrant competition with existing production systems. Therefore, the aim of this project is to utilise the advantages of hairy root cultures of various species, coupled with gene regulation, rhizosecretion and inducibility studies, to increase the production efficiency of vaccines in plant tissues. Various genetic, molecular biological, immunological and biochemical techniques will be used to accomplish this aim.
Supervisors
- Prof. John Hamill
- Dr. Amanda Walmsley
- Dr. Diane Webster
See also
John Hamill Page
Amanda Walmsley Page
